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Stromal gastrointestinal tumor of ileum (clinical case)

Abstract

A small intestine malignant tumor reaches 2,1% in the structure of digestive tract neoplasms. This type of disease presented as duodenal (about 50%), jejunum (30%) and ileum (20%) malignant tumors. These non-epithelial lesions are stromal gastrointestinal tumors (GIST) and recently distinguished as an independent nosological unit, which has individual histological, immunohistochemical and molecular-genetic signs. Diagnostic confirmation of GIST is the measurement of c-Kit expression (CD-117) by immunohistochemistry. The main methods of GIST treatment is surgery and chemotherapy. Our report proves once again, that the diagnosis of small bowel tumor is extremely difficult. We operated a patient with 4th stage of the malignant disease. However, using such a simple method as an ultrasound has allowed to suspect abnormalities in the small intestine. Abdominal CT was performed after that. The key to successful treatment is the use of modern diagnostic methods - transrectal endosonography of pelvis and capsule endoscopy of the small intestine, that allows to diagnose correctly. The main method of treatment is removing of the GIST tumor with lymph node dissection and chemotherapy (Imatinib).

About the Authors

L.D. Roman
Leningrad Regional Oncology Center
Russian Federation


K. G. Shostka
Leningrad Regional Oncology Center
Russian Federation


A. Z. Dovgaluk
Saint-Petersburg Medical Experts’ Continuing Education Institute
Russian Federation


A. A. Sakharov
Leningrad Regional Oncology Center
Russian Federation


R. M. Lukyanchuk
Leningrad Regional Oncology Center
Russian Federation


B. L. Fedotov
Leningrad Regional Oncology Center
Russian Federation


V. G. Anton
Leningrad Regional Oncology Center
Russian Federation


A.A. Gradusov
Leningrad Regional Oncology Center
Russian Federation


References

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Review

For citations:


Roman L., Shostka K.G., Dovgaluk A.Z., Sakharov A.A., Lukyanchuk R.M., Fedotov B.L., Anton V.G., Gradusov A. Stromal gastrointestinal tumor of ileum (clinical case). Ambulatornaya khirurgiya = Ambulatory Surgery (Russia). 2017;(3-4):68-74. (In Russ.)

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ISSN 2712-8741 (Print)
ISSN 2782-2591 (Online)