Preclinical trials of remote noninvasive electromagnetic therapy of purulent wounds on experimental animals

Introduction. The development of new methods for the treatment of purulent wounds of various etiologies in surgical practice is an urgent task.

Aim. Тo study the effect of noninvasive electromagnetic therapy on the healing process of purulent wounds in rabbits.

Materials and methods. The experiment was conducted on the 14 mongrel rabbits. After modeling purulent skin wounds, rabbits were divided into 2 equal groups on day 5. The control group of animals underwent only local wound treatment with saline solution, the experimental group – this manipulation was combined with electromagnetic therapy. The duration of the experiment was 17 days, and the follow-up was 30 days. Clinical monitoring of the animals’ condition was carried out, clinical blood analysis was monitored, and wound discharge was seeded. Wound healing was assessed using the planimetric method. Biometric values were determined in the statistical analysis of the results, and the R.B. Strelkov table was used.

Results and discussion. By day 9 of the experiment, normothermia was noted in the animals in the experimental group, while hyperthermia persisted in 14.3% of the rabbits in the control group. On day 7, in 57.14% of the animals in the control group, the wound decreased by 1.0 cm, and in the experimental group, a decrease from 0.5 to 1.0 cm was detected in 71.42%. On day 14, in the experimental group, in contrast to the control group, no microflora was detected in the wound. On day 5, leukocytosis exceeded the norm by 3.0% in the control group and by 67.7% in the experimental group. In the experimental group, thrombocytosis was observed throughout the experiment, which exceeded the initial values by 70.78% by the end of the experiment.

Conclusions. The use of noninvasive electromagnetic therapy in the treatment of purulent wounds in rabbits accelerates their healing processes.

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