Selection of antibiotics to prevent recurrence of erysipelas
https://doi.org/10.21518/1995-1477-2019-3-4-65-72
Abstract
Erysipelas is an acute infectious disease of streptococcal etiology. Currently, many people lead an active lifestyle, including sports activities both in outdoor areas and in gyms. There is always a risk of various wounds, which are the entry gate for infection, in particular Streptococcus pyogenes. Infection often occurs against the background of weakened immunity. Reduced immune properties can result from frequent stress and chronic fatigue due to severe physical and psycho-emotional stress at work. All these factors in combination create favorable conditions for the development of erysipelas. The peculiarity of face inflammation is that the disease can take a recurrent course. The most important place in the complex treatment of patients with erysipelas is taken by antibiotic therapy. In the treatment of patients in the conditions of the polyclinic it is possible to prescribe antibiotics orally. In the severe course of the disease and the development of complications it is justified to prescribe parenteral therapy. Penicillins are the drugs of choice, because until now penicillins are almost 100% active against Streptococcus pyogenes. During antibiotic therapy it is desirable to combine such properties of the preparation as long-term bactericidal concentration against Streptococcus pyogenes in tissues and, consequently, much lower multiplicity of injections in comparison with benzylpenicillin. These requirements are met by benzathine benzylpenicillin, benzylpenicillin procaine. Based on the results of clinical studies, the advantages of benzathine benzylpenicillin are shown, including in combination with benzylpenicillin procaine to prevent recurrence of erysipelas.
About the Authors
A. V. Rodin
Federal State Budgetary Educational Institution of Higher Professional Education «Smolensk State Medical University» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Cand. of Sci. (Med), Associate Professor of General Surgery with a course of surgery at the Faculty of Additional Professional Education, Head of the Youth Research Center
28, Gagarin Av., Smolensk, 214018, Russia
A. A. Shilina
Federal State Budgetary Educational Institution of Higher Professional Education «Smolensk State Medical University» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Clinical resident
28, Gagarin Av., Smolensk, 214018, Russia
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Review
For citations:
Rodin A.V., Shilina A.A. Selection of antibiotics to prevent recurrence of erysipelas. Ambulatornaya khirurgiya = Ambulatory Surgery (Russia). 2019;(3-4):65-72. (In Russ.) https://doi.org/10.21518/1995-1477-2019-3-4-65-72
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