Rivaroxaban in the outpatient phlebological practice
https://doi.org/10.21518/akh2026-015
Abstract
Nowadays, ambulatory phlebology is rapidly developing. Considering this progress over a period of two to three decades, the quality of diagnosis and treatment of venous disorders has increased exponentially. In addition to the significant shift from inpatient to outpatient settings for interventions on patients with varicose veins, significant advances are being observed across all conditions and their complications where the venous component is involved. Furthermore, in addition to technical, organizational, and hemodynamic advances, more simple therapeutic strategies and minimization of side effects are seen in anticoagulation which is a key component of phlebological care. Rivaroxaban is widely adopted and, due to its convenience, actively used in clinical practice. It has now been well investigated, with numerous studies confirming its efficacy and safety. The article considers the use of rivaroxaban and highlights the importance of quality and production control in example of the Rivaxab®, which is available on the Russian market.
Supporting agencies: The article was prepared with support from Viatris
About the Author
D. A. Borsuk
South Ural State Medical University;
Kazakhstan-Russian Medical University
Russian Federation
Russian Federation
Denis A. Borsuk, Dr. Sci. (Med.), Associate Professor of the Department of Surgery, Institute of Continuing Professional Education, South Ural State Medical University; Professor, Kazakhstan-Russian Medical University
64, Vorovskiy St., Chelyabinsk, 454092,
51/53, Abylay Khan St., Almaty, 050004
References
1. Tauraginskii RA, Lurie F, Agalarov R, Simakov S, Borsuk D. Blood flow from competent tributaries is likely contributor to distally increasing reflux volume in incompetent great saphenous vein. J Vasc Surg Venous Lymphat Disord. 2022;10(1):69–74. https://doi.org/10.1016/j.jvsv.2021.04.010.
2. Lobastov KV, Bondarchuk DV, Borsuk DA, Bredikhin RA, Bukina OV, Pankov AS et al. Diagnosis and treatment of chronic venous obstruction: consensus statement of the Russian experts (Part 1). Khirurg. 2020;(5-6):5–37. (In Russ.) https://doi.org/10.33920/med-15-2003-01.
3. Lobastov KV, Bondarchuk DV, Borsuk DA, Bredikhin RA, Bukina OV, Pankov AS et al. Diagnosis and treatment of chronic venous obstruction: consensus statement of the Russian experts (Part 2). Khirurg. 2020;(7-8):22–55. (In Russ.) https://doi.org/10.33920/med-15-2004-02.
4. Lane RJ, Cuzzilla ML, Harris RA, Phillips MN. Popliteal vein compression syndrome: obesity, venous disease and the popliteal connection. Phlebology. 2009;24(5):201–207. https://doi.org/10.1258/phleb.2008.008039.
5. Dimopoulos C, Papastefanou I, Theodoridis P, Iatrou N, Bisdas T. Incidence and management of symptomatic pelvic venous disorders in patients with lower extremity varicose veins. Phlebology. 2026;41(2):154–162. https://doi.org/10.1177/02683555251351184.
6. Tan M, Lurie F, Bauza Moreno H, Van den Bussche D, Parsi K, Davies AH; UIP. Management of venous leg ulcers. Phlebology. 2024;39(7):488–491. https://doi.org/10.1177/02683555241243167.
7. Mosti G, Benigni JP, Bohbot S, Devoogdt N, Forner-Cordero I, da Matta E et al. Compression terms: Defining terminology of compression therapy — An international compression club consensus document. Phlebology. 2025;40(7):490–495. https://doi.org/10.1177/02683555241313422.
8. Bogachev VYu, Rosukhovski DA, Borsuk DA, Shonov OA, Manjikian HP, Lobastov KV et al. Russian clinical practice guidelines for the management of C1 clinical class of chronic venous disorders (reticular veins and telangiectasias). Ambulatornaya Khirurgiya. 2020;(3-4): 140–206. (In Russ.) https://doi.org/10.21518/18/1995-1477-2020-3-4-140-206.
9. Lee BB, Baumgartner I, Berlien P, Bianchini G, Burrows P, Gloviczki P et al.; International Union of Phlebology. Diagnosis and Treatment of Venous Malformations. Consensus Document of the International Union of Phlebology (IUP): updated 2013. Int Angiol. 2015;34(2):97–149. Available at: https://pubmed.ncbi.nlm.nih.gov/24566499.
10. Executive Committee of the International Society of Lymphology. The Diagnosis and Treatment of Peripheral Lymphedema: 2023 Consensus Document of The International Society of Lymphology. Lymphology. 2023;56(4):133–151. Available at: https://doi.org/10.2458/lymph.6372.
11. Faerber G, Cornely M, Daubert C, Erbacher G, Fink J, Hirsch T et al. S2k guideline lipedema. J Dtsch Dermatol Ges. 2024;22(9):1303–1315. https://doi.org/10.1111/ddg.15513.
12. Борсук ДА, Фокин АА. Пути улучшения результатов миниинвазивного лечения варикозного расширения вен нижних конечностей. М.: ДПК; 2023. 300 с. Режим доступа: https://elibrary.ru/sdacxx.
13. Nicolaides AN, Fareed J, Spyropoulos AC, Kakkar RHL, Antignani PL, Avgerinos E et al. Prevention and management of venous thromboembolism. International Consensus Statement. Guidelines according to scientific evidence. Int Angiol. 2024;43(1):1–222. https://doi.org/10.23736/S0392-9590.23.05177-5.
14. Lobastov KV, Shaldina MV, Matveeva AV, Kovalchuk AV, Borsuk DA, Schastlivtsev IV et al. The correlation between Caprini score and the risk of venous thromboembolism after varicose vein surgery. Int Angiol. 2023;42(6):477–487. https://doi.org/10.23736/S0392-9590.23.05050-2.
15. Lobastov K, Urbanek T, Stepanov E, Lal BK, Marangoni J, Krauss ES et al. The Thresholds of Caprini Score Associated with Increased Risk of Venous Thromboembolism Across Different Specialties: A Systematic Review. Ann Surg. 2023;277(6):929–937. https://doi.org/10.1097/SLA.0000000000005843.
16. Апханова ТВ, Ахметзянов РВ, Ахтямов ИФ, Баринов ВЕ, Бахметьев АС, Белов МВ и др. Тромбоз глубоких вен: клинические рекомендации. 2025. Режим доступа: https://diseases.medelement.com/disease/84-2025/19013.
17. Borsuk DA, Sadek M, Kabnick LS. Current status of endothermal heat induced thrombosis. Int Angiol. 2021;40(4):277–282. https://doi.org/10.23736/S0392-9590.21.04667-8.
18. Fokin AA, Borsuk DA, Kazachkov EL. Efficacy of rivaroxaban for the treatment of endothermal heat-induced thrombosis after endovenous laser ablation. Angiology and Vascular Surgery. 2016;22(4):97–101. (In Russ.) Available at: https://angiolsurgery.org/magazine/2016/4/14.htm.
19. Борсук ДА, Фокин АА. Пути улучшения результатов миниинвазивного лечения варикозного расширения вен нижних конечностей. М.: ДПК Пресс; 2023. 300 с. Режим доступа: // https://elibrary./sdacxx.
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For citations:
Borsuk D.A. Rivaroxaban in the outpatient phlebological practice. Ambulatornaya khirurgiya = Ambulatory Surgery (Russia). 2026;23(1):145-148. (In Russ.) https://doi.org/10.21518/akh2026-015
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