Modern superabsorbent wound dressing in the treatment of complicated forms of diabetic foot syndrome: Clinical research

Introduction. The number of people with diabetes mellitus (DM) in the world is increasing exponentially, most of them are of working age. Diabetic foot syndrome (DFS)leads to theloss of alimb or part of it in 60% of cases. The effective effect of modern sorbent dressings at different stages of the course of the wound process remains the subject of study, controversy and requires deeper awareness and confirmation.

Aim. To detail the effect of modern superabsorbent dressings on the wound process in patients with complicated diabetic foot syndrome.

Materials and methods. A clinical prospective study was conducted to study changes in: laboratory parameters (urea, creatinine, granulocytes, leukocytes, lymphocytes, MID cells); wound area; reduction of wound area as a percentage; healing rate and microbial landscape of wound defects against the background of superabsorbent wound dressing in thelocal treatment of complicated forms of diabetic foot syndrome. A total of 54 patients were selected for the analysis: the main group consisted of 24 people, aged from 49 to 79 years, the average age was 64 ± 11 years, the proportion of men was 41.6% (10/24); the comparison group consisted of 30 people aged from 54 to 75 years, the average age was 65 ± 9 years, the proportion of men was 33.3% (10/30).

Results. Studies of changes inlaboratory parameters: urea, creatinine, granulocytes,leukocytes,lymphocytes, MID cells showed statistically significant differences in both groups at different stages of treatment, mainly on the 14th and 30th day of treatment (4–5 visits). The dynamics of the wound healing rate, a decrease in the wound area as a percentage, a change in the wound area as a whole, as well as a change in the bacterial contamination of the wound were significantly different already on the 7th day of treatment.

Conclusions. The expediency of using Zetuvit Plus Silicone sorbent dressings was confirmed by a study of the dynamics of changes in laboratory parameters, the quantitative and qualitative microbiallandscape of trophic ulcers against the background of diabetes mellitus, and indicators of soft tissue regeneration processes.

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