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Modern and promising ways of bowel preparation for instrumental research

https://doi.org/10.21518/1995-1477-2021-18-1-91-102

Abstract

A review is presented to summarize data on intestinal preparation approaches and methods for research. The historical background and main stages in the development of the intestinal lavage method are highlighted, and traditional and modern methods of evaluating its effectiveness are characterized. Dietary recommendations and information about the basic drugs used nowadays in preparation of the intestine for instrumental research are adduced. Clinical aspects of different types of osmotic action of drugs are considered. The composition of laxatives for salt and electrolyte components in terms of potential benefit and risk in patients is analyzed. The main positions of the current recommendations of domestic, European and American expert communities concerning the discussed topic are taken into account. Demonstrated “no less efficacy” of sulfate solution compared with macrogol in adult patients. Clinical case is presented: patient A., 22 years old, admitted to the clinic with complaints of recurrent pain in the left abdomen, frequent stools, sometimes with blood, loss of hair, flaky spots on the skin of the upper extremities. The patient was prepared for the examination – colon cleansing with a sulfate drug, endoscopic examination of the colon - colonoscopy was performed. Diagnosis: nonspecific ulcerative colitis. The treatment scheme is presented, clinical remission of the disease is achieved.

About the Authors

E. V. Kanner
Central Research Institute of Epidemiology of Rospotrebnadzor
Russian Federation

Ekaterina V. Kanner, Cand. Sci. (Med.), Senior Researcher of the  Clinical Department of Infectious Pathology

3а, Novogireevskaya St., Moscow, 111123



M. L. Maximov
Kazan State Medical Academy; Pirogov Russian National Research Medical University
Russian Federation

Maxim L. Maximov, Dr. Sci. (Med.), Chief Freelance Specialist  Clinical Pharmacologist of the Ministry of health of the Republic  of Tatarstan, head of the Department of Clinical Pharmacology  and Pharmacotherapy

36, Butlerov St., Kazan, 420012;

Professor of the Department of Pharmacology, Paediatric Faculty

1, Ostrovityanov St., Moscow, 117997



A. S. Ermolaeva
Sechenov First Moscow State Medical university (Sechenov university)
Russian Federation

Anna S. Ermolaeva, Cand. Sci. (Med.), Associate Professor of the  Department of Clinical Pharmacology and Propaedeutics of Internal Diseases

8, Bldg. 2, Trubetskaya St., Moscow, 119991



I. D. Kanner
Lomonosov Moscow State University
Russian Federation

Ilya D. Kanner, a third-year student

1, Leninskie Gory, Moscow, 119991



N. M. Lapkin
Yaroslavl State Medical University
Russian Federation

Nikita M. Lapkin, a fifth-year student

5, Revolutsionnaya St., Yaroslavl, 150000



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Review

For citations:


Kanner E.V., Maximov M.L., Ermolaeva A.S., Kanner I.D., Lapkin N.M. Modern and promising ways of bowel preparation for instrumental research. Ambulatornaya khirurgiya = Ambulatory Surgery (Russia). 2021;18(1):91-102. (In Russ.) https://doi.org/10.21518/1995-1477-2021-18-1-91-102

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