<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">asurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Амбулаторная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8741</issn><issn pub-type="epub">2782-2591</issn><publisher><publisher-name>ООО «ГРУППА РЕМЕДИУМ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">asurgery-68</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФЛЕБОЛОГИЯ | АНГИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHLEBOLOGY | ANGIOLOGY</subject></subj-group></article-categories><title-group><article-title>Возможности фармакотерапии нарушений венозного оттока и микроциркуляции при хронических заболеваниях вен нижних конечностей. По мотивам консенсуса Международного союза флебологов (UIP)</article-title><trans-title-group xml:lang="en"><trans-title>The prospects for pharmacotherapy of disorders of venous outflow and microcirculation in chronic venous disease. Based on the consensus of the international union of phlebology (UIP)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богачев</surname><given-names>B. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogachev</surname><given-names>V. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болдин</surname><given-names>Б. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Boldin</surname><given-names>B. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родионов</surname><given-names>C. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rodionov</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дженина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhenina</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый флебологический центр; РНРМУ им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Phlebology Centre; RNRMU named after N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>РНРМУ им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>RNRMU named after N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый флебологический центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Phlebology Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2017</year></pub-date><volume>0</volume><issue>1-2</issue><fpage>23</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Богачев B.Ю., Болдин Б.В., Родионов C.В., Дженина О.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Богачев B.Ю., Болдин Б.В., Родионов C.В., Дженина О.В.</copyright-holder><copyright-holder xml:lang="en">Bogachev V.Y., Boldin B.V., Rodionov S.V., Dzhenina O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.a-surgeon.ru/jour/article/view/68">https://www.a-surgeon.ru/jour/article/view/68</self-uri><abstract><p>Хронические заболевания вен (ХЗВ) представляют собой наиболее частую патологию периферических сосудов, в развитии которой участвуют различные патогенетические механизмы, приводящие к функциональным и структурным нарушениям венозной и лимфатической системы нижних конечностей. Одним из актуальных направлений в коррекции различных стадий и форм ХЗВ служит фармакологическая терапия с первоочередным использованием флеботропных препаратов (син.: флебопротекторы, веноактивные препараты (ВАП)). В настоящем обзоре представлены самые современные данные, касающиеся влияния флеботропных препаратов на макро- и микрогемодинамику при ХЗВ.</p></abstract><trans-abstract xml:lang="en"><p>Chronic venous diseases (CVDs) represent the most common pathology of peripheral vessels, the development of which involves different patho-genetic mechanisms leading to functional and structural abnormalities of the venous and lymphatic system of the lower extremities. One of the current trends in the correction of different stages and forms of CVD is pharmacological therapy which prioritizes the use of phlebotropic drugs (syn.: phleboprotectors, venoactive drugs (VADs)). The review summarizes the most recent data concerning the effect of phlebotropic drugs on macro- and microhemodynamics of CVDs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронические заболевания вен</kwd><kwd>флеботропные препараты</kwd><kwd>МОФФ</kwd><kwd>Детралекс</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lee B-B, NicoLaides A, Myers K et aL. Venous hemodynamic changes in lower limb venous disease: the UIP consensus according to scientific evidence (Chapter 6. Effect of pharmacotherapy on venous tone, flow and the microcirculation). International angi-ology, 2016, 35 (3): 299-310.</mixed-citation><mixed-citation xml:lang="en">Lee B-B, NicoLaides A, Myers K et aL. Venous hemodynamic changes in lower limb venous disease: the UIP consensus according to scientific evidence (Chapter 6. Effect of pharmacotherapy on venous tone, flow and the microcirculation). International angi-ology, 2016, 35 (3): 299-310.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
