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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">asurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Амбулаторная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8741</issn><issn pub-type="epub">2782-2591</issn><publisher><publisher-name>ООО «ГРУППА РЕМЕДИУМ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">asurgery-54</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФЛЕБОЛОГИЯ | АНГИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHLEBOLOGY | ANGIOLOGY</subject></subj-group></article-categories><title-group><article-title>Тромбофлебит (тромбоз поверхностных вен): современные стандарты диагностики и лечения</article-title><trans-title-group xml:lang="en"><trans-title>Thrombophlebitis (superficial veins thrombosis): modern standards of diagnostics and therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богачев</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogachev</surname><given-names>V. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болдин</surname><given-names>Б. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Boldin</surname><given-names>B. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дженина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhenina</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобанов</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lobanov</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian Scientific and Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Флебологический Центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Phlebologic Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>3-4</issue><fpage>16</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Богачев В.Ю., Болдин Б.В., Дженина О.В., Лобанов В.Н., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Богачев В.Ю., Болдин Б.В., Дженина О.В., Лобанов В.Н.</copyright-holder><copyright-holder xml:lang="en">Bogachev V.Y., Boldin B.V., Dzhenina O.V., Lobanov V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.a-surgeon.ru/jour/article/view/54">https://www.a-surgeon.ru/jour/article/view/54</self-uri><abstract><p>Тромбофлебит (воспаление и тромбоз поверхностных вен любой локализации) является достаточно частым патологическим состоянием. В специальной литературе используют понятия «варикотромбофлебит» для обозначения тромбоза и воспаления варикозной вены, а также «флебит» - воспаление поверхностной вены без тромбоза. Традиционным заблуждением служит представление о тромбофлебите как о локальном, самоограниченном процессе, который, в отличие от тромбоза глубоких вен (ТГВ), не несет серьезных опасностей для жизни и здоровья пациентов. Такая позиция глубоко ошибочна.</p></abstract><trans-abstract xml:lang="en"><p>Thrombophlebitis (inflammation and thrombosis of superficial veins of any localization) is a frequent pathologic state. In the special literature they use notions varicothrom-bophlebitis for designation of thrombosis and inflammation of the varicose vein as well as phlebitis - inflammation of the superficial vein without thrombosis. A traditional error is idea of thrombophlebitis as of local, self-limited process that as opposed to deep vein thrombosis has no serious dangers for life and health of patients. This position is a profound mistake hrombophlebitis (inflammation and thrombosis of superficial veins of any localization) is a frequent pathologic state. In the special literature they use notions varicothrom-bophlebitis for designation of thrombosis and inflammation of the varicose vein as well as phlebitis - inflammation of the superficial vein without thrombosis. A traditional error is idea of thrombophlebitis as of local, self-limited process that as opposed to deep vein thrombosis has no serious dangers for life and health of patients. This position is a profound mistake</p></trans-abstract><kwd-group xml:lang="ru"><kwd>тромбофлебит</kwd><kwd>факторы риска</kwd><kwd>тромбоз глубоких вен</kwd><kwd>тромбоэмболия легочной артерии</kwd><kwd>лечение</kwd><kwd>низкомолекулярные гепарины</kwd><kwd>исследование RASET</kwd><kwd>ривароксабан</kwd><kwd>thrombophlebitis</kwd><kwd>risk factors</kwd><kwd>deep vein thrombosis</kwd><kwd>pulmonary artery thromboembolia</kwd><kwd>therapy</kwd><kwd>low-molecular heparins</kwd><kwd>RASETstudy</kwd><kwd>Rivaroxaban</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Decousus H, Quere I, Presles E, Becker F, Barrellier MT, Chanut M, Gillet JL, Guenneguez H, Leandri C, Mismetti P, Pichot O, Leizorovicz A. Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study. Ann Intern Med, 2010, 152(4): 218-224.</mixed-citation><mixed-citation xml:lang="en">Decousus H, Quere I, Presles E, Becker F, Barrellier MT, Chanut M, Gillet JL, Guenneguez H, Leandri C, Mismetti P, Pichot O, Leizorovicz A. Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study. Ann Intern Med, 2010, 152(4): 218-224.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Karathanos C, Exarchou M, Tsezou A, Kyriakou D, Wittens C, Giannoukas A. Factors associated with the development of superficial vein thrombosis in patients with varicose veins. Thromb Res, 2013, 132(1): 47-50.</mixed-citation><mixed-citation xml:lang="en">Karathanos C, Exarchou M, Tsezou A, Kyriakou D, Wittens C, Giannoukas A. Factors associated with the development of superficial vein thrombosis in patients with varicose veins. Thromb Res, 2013, 132(1): 47-50.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Decousus H, Bertoletti L, Frappe P. Spontaneous acute superficial vein thrombosis of the legs: do we really need to treat? J Thromb Haemost. 2015, 13(Suppl 1): 230-237.</mixed-citation><mixed-citation xml:lang="en">Decousus H, Bertoletti L, Frappe P. Spontaneous acute superficial vein thrombosis of the legs: do we really need to treat? J Thromb Haemost. 2015, 13(Suppl 1): 230-237.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Galanaud JP, Genty C, Sevestre MA, Brisot D, Lausecker M, Gillet JL, Rolland C, Righini M, Leftheriotis G, Bosson JL, Quere I.Predictive factors for concurrent deep-vein thrombosis and symptomatic venous thromboembolic recurrence in case of superficial venous thrombosis. The OPTIMEV study. Thromb Haemost. 2011, 105(1): 31-39.</mixed-citation><mixed-citation xml:lang="en">Galanaud JP, Genty C, Sevestre MA, Brisot D, Lausecker M, Gillet JL, Rolland C, Righini M, Leftheriotis G, Bosson JL, Quere I.Predictive factors for concurrent deep-vein thrombosis and symptomatic venous thromboembolic recurrence in case of superficial venous thrombosis. The OPTIMEV study. Thromb Haemost. 2011, 105(1): 31-39.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Frappe P, Buchmuller-Cordier A, Bertoletti L, Bonithon-Kopp C, Couzan S, Lafond P, Leizorovicz A, Merah A, Presles E, Preynat P, Tardy B, Decousus H. Annual diagnosis rate of superficial vein thrombosis of the lower limbs: the STEPH community based study. J Thromb Haemost, 2014, 12(6): 831-838.</mixed-citation><mixed-citation xml:lang="en">Frappe P, Buchmuller-Cordier A, Bertoletti L, Bonithon-Kopp C, Couzan S, Lafond P, Leizorovicz A, Merah A, Presles E, Preynat P, Tardy B, Decousus H. Annual diagnosis rate of superficial vein thrombosis of the lower limbs: the STEPH community based study. J Thromb Haemost, 2014, 12(6): 831-838.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">STENOX study group. A pilot randomized double-blind comparison of a low-molecular-weight heparin, a nonsteroidal anti-inflammatory agent, and placebo in the treatment of super- ficial vein thrombosis. Arch Intern Med, 2003, 163(14): 1657-1663.</mixed-citation><mixed-citation xml:lang="en">STENOX study group. A pilot randomized double-blind comparison of a low-molecular-weight heparin, a nonsteroidal anti-inflammatory agent, and placebo in the treatment of super- ficial vein thrombosis. Arch Intern Med, 2003, 163(14): 1657-1663.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Prandoni P, Tormene D, Pesavento R. High vs. low doses of low-molecular-weight heparin for the treatment of superficial vein thrombosis of the legs: a double-blind, randomized trial. J Thromb Haemost, 2005, 3(6): 1152-1157.</mixed-citation><mixed-citation xml:lang="en">Prandoni P, Tormene D, Pesavento R. High vs. low doses of low-molecular-weight heparin for the treatment of superficial vein thrombosis of the legs: a double-blind, randomized trial. J Thromb Haemost, 2005, 3(6): 1152-1157.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Gillet J-L. Management of superficial vein thrombosis of the lower limbs: update and current recommendations. Phlebolymphology, 2015, 22: 82-89.</mixed-citation><mixed-citation xml:lang="en">Gillet J-L. Management of superficial vein thrombosis of the lower limbs: update and current recommendations. Phlebolymphology, 2015, 22: 82-89.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kearon C, Akl EA, Ornelas J et al. Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. Chest, 2016;149(2): 315-352.</mixed-citation><mixed-citation xml:lang="en">Kearon C, Akl EA, Ornelas J et al. Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. Chest, 2016;149(2): 315-352.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Decousus H, Prandoni P, Mismetti P, Bauersachs RM, Boda Z, Brenner B, Laporte S, Matyas L, Middeldorp S, Sokurenko G, Leizorovicz A. Fondaparinux for the treatment of super- ficial-vein thrombosis in the legs. N Engl J Med. 2010, 363(13): 1222-1232.</mixed-citation><mixed-citation xml:lang="en">Decousus H, Prandoni P, Mismetti P, Bauersachs RM, Boda Z, Brenner B, Laporte S, Matyas L, Middeldorp S, Sokurenko G, Leizorovicz A. Fondaparinux for the treatment of super- ficial-vein thrombosis in the legs. N Engl J Med. 2010, 363(13): 1222-1232.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Cosmi B, Filippini M, Tonti D, Avruscio G, Ghirarduzzi A, Bucherini E, Camporese G, Imberti D, Palareti G. A randomized double-blind study of low-molecular-weight heparin (parnaparin) for superficial vein thrombosis: STEFLUX (Superficial ThromboEmbolism and Fluxum). J Thromb Haemost, 2012, 10(6): 1026-1035.</mixed-citation><mixed-citation xml:lang="en">Cosmi B, Filippini M, Tonti D, Avruscio G, Ghirarduzzi A, Bucherini E, Camporese G, Imberti D, Palareti G. A randomized double-blind study of low-molecular-weight heparin (parnaparin) for superficial vein thrombosis: STEFLUX (Superficial ThromboEmbolism and Fluxum). J Thromb Haemost, 2012, 10(6): 1026-1035.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Blondon M, Righini M, Bounameaux H, Veenstra DL. Fondaparinux for isolated superficial-vein thrombosis of the legs: a cost-effectiveness analysis. Chest, 2011, 141(2): 321-329.</mixed-citation><mixed-citation xml:lang="en">Blondon M, Righini M, Bounameaux H, Veenstra DL. Fondaparinux for isolated superficial-vein thrombosis of the legs: a cost-effectiveness analysis. Chest, 2011, 141(2): 321-329.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Werth S, Bauersachs R, Gerlach H, Rabe E, Schellong S, Beyer-Westerndorf J. Superficial vein thrombosis treated for 45 days with rivaroxaban versus fondaparinux: rationale and design of the SURPRISE trial. J Thromb Thrombolysis, 2016, 42: 197-204.</mixed-citation><mixed-citation xml:lang="en">Werth S, Bauersachs R, Gerlach H, Rabe E, Schellong S, Beyer-Westerndorf J. Superficial vein thrombosis treated for 45 days with rivaroxaban versus fondaparinux: rationale and design of the SURPRISE trial. J Thromb Thrombolysis, 2016, 42: 197-204.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Einstein-Investigators Bauersachs R, Berkowitz SD, Brenner B, Buller HR, Decousus H, Gallus AS, Lensing AW, Misselwitz F, Prins MH, Raskob GE, Segers A, Verhamme P, Wells P, Agnelli G, Bounameaux H, Cohen A, Davidson BL, Piovella F, Schellong S. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med, 2010, 363(26): 2499-2510.</mixed-citation><mixed-citation xml:lang="en">Einstein-Investigators Bauersachs R, Berkowitz SD, Brenner B, Buller HR, Decousus H, Gallus AS, Lensing AW, Misselwitz F, Prins MH, Raskob GE, Segers A, Verhamme P, Wells P, Agnelli G, Bounameaux H, Cohen A, Davidson BL, Piovella F, Schellong S. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med, 2010, 363(26): 2499-2510.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Einstein-PE-Investigators Buller HR, Prins MH, Lensin AW, Decousus H, Jacobson BF, Minar E, Chlumsky J, Verhamme P, Wells P, Agnelli G, Cohen A, Berkowitz SD, Bounameaux H, Davidson BL, Misselwitz F, Gallus AS, Raskob GE, Schellong S, Segers A. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med, 2012, 366(14): 1287-1297.</mixed-citation><mixed-citation xml:lang="en">Einstein-PE-Investigators Buller HR, Prins MH, Lensin AW, Decousus H, Jacobson BF, Minar E, Chlumsky J, Verhamme P, Wells P, Agnelli G, Cohen A, Berkowitz SD, Bounameaux H, Davidson BL, Misselwitz F, Gallus AS, Raskob GE, Schellong S, Segers A. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med, 2012, 366(14): 1287-1297.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
