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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">asurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Амбулаторная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8741</issn><issn pub-type="epub">2782-2591</issn><publisher><publisher-name>ООО «ГРУППА РЕМЕДИУМ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/akh2023-016</article-id><article-id custom-type="elpub" pub-id-type="custom">asurgery-397</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОКТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PROCTOLOGY</subject></subj-group></article-categories><title-group><article-title>Пикосульфат натрия в клинической практике хирурга</article-title><trans-title-group xml:lang="en"><trans-title>Sodium picosulfate in the clinical practice of a surgeon</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1312-1971</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матвеев</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Matveev</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матвеев Иван Анатольевич, д.м.н., доцент, заведующий кафедрой факультетской хирургии; врач-колопроктолог </p><p>625023, Тюмень, ул. Одесская, д. 54;625023, Тюмень, ул. Котовского, д. 55</p></bio><bio xml:lang="en"><p>Ivan A. Matveev, Dr. Sci. (Med.), Associate Professor, Head of the Department of Faculty Surgery; Coloproctologist </p><p>54, Odesskaya St., Tyumen, 625023;55, Kotovskogo St., Tyumen, 625023</p></bio><email xlink:type="simple">matveevia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Липовой</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lipovoy</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Липовой Сергей Владимирович, заведующий отделением гнойной хирургии </p><p>625023, Тюмень, ул. Котовского, д. 55</p></bio><bio xml:lang="en"><p>Sergey V. Lipovoy, Head of the Department of Purulent Surgery </p><p>55, Kotovskogo St., Tyumen, 625023</p></bio><email xlink:type="simple">s.lipovoy@tokb.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козлов Михаил Петрович, врач-эндоскопист отделения эндоскопии </p><p>625023, Тюмень, ул. Котовского, д. 55</p></bio><bio xml:lang="en"><p>Mikhail P. Kozlov, Endoscopist, Endoscopy Department </p><p>55, Kotovskogo St., Tyumen, 625023</p></bio><email xlink:type="simple">mkozlov2013@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4069-8071</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поварнин</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Povarnin</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Поварнин Николай Николаевич, врач-колопроктолог </p><p>625000, Тюмень, ул. Водопроводная, д. 36/1б</p></bio><bio xml:lang="en"><p>Nikolay N. Povarnin, Coloproctologist </p><p>36/1b, Vodoprovodnaya St., Tyumen, 625000</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тюменский государственный медицинский университет;&#13;
Областная клиническая больница №1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University;&#13;
Tyumen Regional Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Областная клиническая больница №1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen Regional Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>НаноМед Плюс</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NanoMed Plus</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>27</day><month>11</month><year>2023</year></pub-date><volume>20</volume><issue>2</issue><fpage>135</fpage><lpage>143</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Матвеев И.А., Липовой С.В., Козлов М.П., Поварнин Н.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Матвеев И.А., Липовой С.В., Козлов М.П., Поварнин Н.Н.</copyright-holder><copyright-holder xml:lang="en">Matveev I.A., Lipovoy S.V., Kozlov M.P., Povarnin N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.a-surgeon.ru/jour/article/view/397">https://www.a-surgeon.ru/jour/article/view/397</self-uri><abstract><p>Пикосульфат, производное дифенилметана, относящееся к группе стимулирующих слабительных, достаточно широко применяется в хирургии при различных нарушениях эвакуации содержимого толстой кишки ввиду эффективности, безопасности применения и легкости подбора дозировки, возможности его комбинаций с другими слабительными препаратами. Значительно большая потребность в нем существует при скрининге колоректального рака, когда подготовка толстой кишки проводится пикосульфатом натрия в комбинации с другими осмотическими слабительными, чаще всего полиэтиленгликолем, что позволяет применять меньшие объемы раствора. Этот способ очистки толстой кишки, по данным литературы, применяется наиболее часто, что связано, как показали и наши наблюдения, с лучшей приверженностью обследуемых приему малых объемов жидкости. Статья освещает данные литературы, также авторы приводят собственный опыт – клинический пример лечения пациентки 30 лет с диагнозом «наружный и внутренний геморрой I стадии». Под местной анестезией была выполнена лазерная абляция внутренних и иссечение наружных геморроидальных узлов. В послеоперационном периоде наряду с топическими средствами и обезболиванием в терапию был включен Регулакс® Пикосульфат. В результате у пациентки была комфортная малоболезненная дефекация на следующие сутки после операции. Коррекция стула при помощи слабительного производилась в течение недели. В заключение авторы обращают внимание на то, что повышение комплаенса пациентов при подготовке толстой кишки к обследованию ведет к ее более качественной очистке и достижению лучших результатов при проведении колоноскопии. Поэтому Регулакс® Пикосульфат в комбинации с другими слабительными при подготовке пациентов, в частности при проведении скрининга колоректального рака, где он используется чаще всего, касается колоссального количества пациентов, поэтому проблема дальнейшего изучения его применения является социально значимой.</p></abstract><trans-abstract xml:lang="en"><p>Picosulfate, a diphenylmethane derivative, belongs to a group of drugs called stimulant laxatives. It is widely used in surgery to treat various colon evacuation disorders due to its effectiveness, safety of use and ease of dosage selection, as well as the option to combine with other laxatives. It is administered much more frequently for colorectal cancer screening, when the colon is prepared using sodium picosulfate combined with other osmotic laxatives, most often polyethylene glycol, which allows to use smaller volumes of solution. According to the literature, this method for cleaning the colon is used most often, which is associated with better adherence of patients to the intake of small volumes of liquid, as shown by our observations. The article highlights the literature data, and the authors also present their own experience – a clinical case report of the treatment of a 30-year-old patient diagnosed with grade I external and internal hemorrhoids. Laser ablation of internal and excision of external hemorrhoids was performed under local anesthesia. Regulax® Picosulfate was included in the therapy in the postoperative period, along with topical and pain relief drugs. As a result, the patient had a comfortable, not very painful bowel movement on the following day after the surgery. The laxative was used to manage stool for a week. In conclusion, the authors draw attention to the fact that increased patient compliance in preparing the colon for examination leads to better cleaning and more informative results during colonoscopy. Therefore, Regulax® Picosulfate combined with other laxatives to prepare a patient for examination, in particular colorectal cancer screening, where it is used most often, applies to a huge number of patients, so the problem of further study of its use is socially significant.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>толстая кишка</kwd><kwd>нарушение эвакуаторной функции</kwd><kwd>лечение</kwd><kwd>подготовка кишечника</kwd><kwd>пикосульфат натрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colon</kwd><kwd>evacuation function disorder</kwd><kwd>treatment</kwd><kwd>bowel preparation</kwd><kwd>sodium picosulfate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лазебник ЛБ, Туркина СВ, Голованова ЕВ, Ардатская МД, Остроумова ОД, Комиссаренко ИА и др. Запоры у взрослых. 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