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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">asurgery</journal-id><journal-title-group><journal-title xml:lang="ru">Амбулаторная хирургия</journal-title><trans-title-group xml:lang="en"><trans-title>Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8741</issn><issn pub-type="epub">2782-2591</issn><publisher><publisher-name>ООО «ГРУППА РЕМЕДИУМ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/1995-1477-2019-1-2-34-37</article-id><article-id custom-type="elpub" pub-id-type="custom">asurgery-134</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФЛЕБОЛОГИЯ | АНГИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHLEBOLOGY | ANGIOLOGY</subject></subj-group></article-categories><title-group><article-title>Возможности терапии симптомов хронических заболеваний вен нижних конечностей</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of treatment of symptoms of chronic diseases of lower limbs veins</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудыкин</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudykin</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кудыкин Максим Николаевич – доктор медицинских наук, исполнительный директор общественной организации «Ассоциация ангиологов, флебологов и сосудистых хирургов Нижегородской области»; вице-президент  «Ассоциации флебологов России».</p><p>603141, Нижегородская область, Нижний Новгород, ул. Геологов, д.1, пом. п 29.</p></bio><bio xml:lang="en"><p>Kudykin Maxim Nikolayevich – Dr. of Sci. (Med), Executive Director of the public organization «Association of Angiologists, Phlebologists and Vascular Surgeons of Nizhny Novgorod Region»; Vice-President of «Association of Phlebologists of Russia».</p><p>603141, Nizhny Novgorod Region, Nizhny Novgorod, Geologov St., 1, bldg. 29.</p></bio><email xlink:type="simple">mady5@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ассоциация ангиологов, флебологов и сосудистых хирургов Нижегородской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Association of Angiologists, Phlebologists and Vascular Surgeons of Nizhny Novgorod Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>12</day><month>04</month><year>2019</year></pub-date><volume>0</volume><issue>1-2</issue><fpage>34</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кудыкин М.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Кудыкин М.Н.</copyright-holder><copyright-holder xml:lang="en">Kudykin M.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.a-surgeon.ru/jour/article/view/134">https://www.a-surgeon.ru/jour/article/view/134</self-uri><abstract><p>В обзоре представлены  литературные данные об эпидемиологии хронических заболеваний вен (ХЗВ) и хронической венозной недостаточности (ХВН). Приводятся основные подходы к выбору консервативной  терапии ХЗВ и ХВН. Обосновывается рациональность симптоматического лечения этой категории пациентов. Приводятся сведения о клинических эффектах и механизмах их реализации  у препарата добезилат  кальция.  Освещаются результаты доклинических и клинических исследований  по оценке эффективности и безопасности добезилата кальция в отношении симптоматического лечения ХЗВ и ХВН. На основании анализа литературных источников приводится вывод о целесообразности широкого применения добезилата кальция во флебологической практике.</p></abstract><trans-abstract xml:lang="en"><p>The review presents literature on the epidemiology  of chronic venous diseases  (CVD) and chronic venous insufficiency (CVI). The main approaches to the  choice of conservative  therapy  for CVD and CVI are presented. The rationality of symptomatic treatment of this category of patients is justified. Data on clinical effects  and mechanisms  of their realization in the preparation of calcium dobesilate are given. The results  of preclinical and clinical studies to assess the efficacy and safety of calcium dobesilate in relation to the  symptomatic treatment of CVD and CVI are presented. On the  basis  of the  analysis  of literary  sources  the  conclusion  on expediency of wide application of calcium dobesilate in phlebological practice is presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронические заболевания вен</kwd><kwd>хроническая венозная недостаточность</kwd><kwd>кальция добезилат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic vein diseases</kwd><kwd>chronic venous insufficiency</kwd><kwd>calcium dobesilate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rabe E., Pannier F. Epidemiology of chronic venous disorders. In: Gloviczki P ed. 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